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Comparison of Siemens Vista and i-STAT Troponin I

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One of my difficulties when attempting method comparisons per CAP COM.04250 has been the TropI run in chemistry on the Siemens Vista and on the  i-STAT. Does anyone else have this combination of instruments? How do you compare the results?

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I had this combination at a previous facility.  I had the ER staff run the troponin on the iSTAT immediately at draw and then pulled the lab ordered Vista result.  I found that the results correlated well with the understanding that the Vista Troponin rose faster than the iSTAT.
example: 
iSTAT    Vista
0.05       0.07
1.0           1.5
10            15
Of course you need to stress to the users that serial comparisons between the iSTAT and Lab results can not be done.

Also, there were outliers: istat reports negative to low and the Vista reports out elevated.  When investigating these you will find that the patients are chronically elevated, CHF, hypertensive, liver/kidney patients. 

Thank you!

We do a qualitative comparison since the positive cut off is so different.  We do not always match 100%, but there is often a clinical explanation for that or it is very close to the cut-off for the i-STAT.

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Kelsey M
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